This is a comment that I had posted to a Site discussing the problems that ensue when people interfere with Nature, specifically Insulin:
The missing C-peptide that is now a part of genetically altered insulin does indeed, blunt the feelings such as tachycardia associated with on-coming Hypoglycemia.
This causes problems in two ways:
1. The longevity of Diabetes will by itself cause Hypoglycemia Unawareness.
2. The taking out of C-peptide in genetically altered insulin will also be responsible for the "blunting effect" so that the person is unable to remedy the situation in time.
When you have these things occurring together as well as the possible addition of a Beta-Blocker than the potential for a very dangerous situation exists. It leaves the person only being able to tell if their blood sugars are low by means of a meter reading. The reality is, that not everyone can afford the Continuous Glucose Monitor or be forced to wear one.
Logically, it would be much simpler and wiser to make C-peptide available as a separate vial that could be injected along w/insulin.
Realistically, there is too much time and money already invested in the manufacturing process of insulin and that it was the only way to have it available in third world countries that are lacking enough animals and money to supply insulin or/and do not have the resources available to extract porcine/bovine insulin.
The Genie(C-peptide) cannot be put back in the bottle, but it can be put into a separate vial and made available since it offers much more to a person with Diabetes than a heightened awareness of impending Hypoglycemia. These are neuro, nephro, micro/macro vascular and cardio protective features so as to minimize or protect against the ravages of Complications associated with Long-term Diabetes despite good "numbers".
As WE all know, Diabetes does not go away and as such, WE have to do everything possible to make living with it, in our best interest. We have to be able to control it rather than the other way around.
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- I do not give up my Autonomy,especially to the Medical Profession. Passionate, Creative, Able to see Beauty within Simplicity, I Am Not A Diabetic, rather I have Diabetes (there is a big difference between the two on many levels).Type 1 Diabetes since 5 years of age. Belief in G-D